Wednesday, February 6, 2008

Cardiomyopathy

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Cardiomyopathy literally means "heart muscle disease" (Myo= muscle, pathy= disease) It is the deterioration of the function of the myocardium (i.e., the actual heart muscle) for any reason. People with cardiomyopathy are often at risk of arrhythmia and/or sudden cardiac death.
Extrinsic cardiomyopathies - cardiomyopathies where the primary
pathology is outside the myocardium itself. Most cardiomyopathies are extrinsic, because by far the most common cause of a cardiomyopathy is ischemia. The World Health Organization calls these specific cardiomyopathies[citation needed]:
Alcoholic cardiomyopathy
Coronary artery disease
Congenital heart disease - see below
Nutritional diseases affecting the heart
Ischemic (or ischaemic) cardiomyopathy
Hypertensive cardiomyopathy
Valvular cardiomyopathy - see also Valvular heart disease below
Inflammatory cardiomyopathy - see also Inflammatory heart disease below
Cardiomyopathy secondary to a systemic metabolic disease
Intrinsic cardiomyopathies - weakness in the muscle of the heart that is not due to an identifiable external cause.
Dilated cardiomyopathy (DCM) - most common form, and one of the leading indications for heart transplantation. In DCM the heart (especially the left ventricle) is enlarged and the pumping function is diminished.
Hypertrophic cardiomyopathy (HCM or HOCM) - genetic disorder caused by various mutations in genes encoding sarcomeric proteins. In HCM the heart muscle is thickened, which can obstruct blood flow and prevent the heart from functioning properly.
Arrhythmogenic right ventricular cardiomyopathy (ARVC) - arises from an electrical disturbance of the heart in which heart muscle is replaced by fibrous scar tissue. The right ventricle is generally most affected.
Restrictive cardiomyopathy (RCM) - least common cardiomyopathy. The walls of the ventricles are stiff, but may not be thickened, and resist the normal filling of the heart with blood. ** Noncompaction Cardiomyopathy - the left ventricle wall has failed to properly grow from birth and such has a spongy appearance when viewed during an echocardiogram.

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